OXPzero™ NSAIDs are novel salts of ibuprofen, naproxen and diclofenac, the most commonly used drugs to treat pain and inflammation. The OXPzero™ technology enables major growth opportunities in both over-the-counter and prescription medicine markets. Clinical results have already demonstrated these compounds to be far safer than conventional NSAIDs, without the need for complex formulation technologies or poly pharmacy approaches.
In addition, these compounds have very rapid absorption, without compromising safety, making them perfect for both acute and chronic pain markets.
Our lead product OXPzero™ Ibuprofen is a differentiated, superior form of ibuprofen delivering a range of benefits over standard ibuprofen. OXPzero™ Ibuprofen has been proven to:
- deliver major reduction in gastrointestinal (GI) mucosal damage on Rx dose: increase millions of usage occasions
- significantly taste-mask the bitterness/burn of ibuprofen: opens up potential for new NPD and EPD pipeline
- deliver an attractive PK profile bioequivalent to Ibuprofen free acid reference for AUC and Cmax
The OXPZero™ technology is protected by a comprehensive set of patent families filed in major jurisdictions around the globe. If you are interested in learning more about our OXPzero™ NSAIDs pipeline and want to discuss partnership opportunities for your market, please contact us.
OXP Soft Chew Matrix
Unlike regular coated tablet or compression tablet technologies, OXPChew™ is a solid state suspension that produces ‘Soft Chews’ where an insoluble active ingredient is suspended in a semi-solid matrix. The OXPChew™ technology provides for rapid dissolution profiles of active ingredients with superior organoleptic mouth feel and taste. The OXPChew™ technology is protected by a granted EU patent and extensive formulation and manufacturing know-how.
The manufacturing process is such that the active ingredients are uniformly and substantially distributed or dispersed over the matrix. The matrix primarily composed of soluble fibers dissolves quickly at stomach conditions, helps the ‘wetting’ of each individual particle, and releases them in conditions ideal for solubilisation.
The The OXPChew™ technology is used in our product Ellactiva® Calcium Chews resulting in significantly enhanced speed of dissolution and total dissolution of calcium relative to leading calcium supplements including tablets and chewable tablets.